Aging is a multifactorial process. Maximal lifespan is highly variable among people, and is related to genes, lifestyle and chance in equal parts.
There is no question lifestyle plays a role and diet and exercise account for a significant portion of that.
Many dietary agents have been reported to extend lifespan in animals. Chief among them include resveratrol, green tea, and curcumin.
Researchers funded by the NIH set out to determine if any of these agents and also including oxaloacetic acid and medium chain fatty acids would extend the lifespan of laboratory mice.
In the trial researchers at 3 institutions independent tested the 5 agents on a groups of about 200 genetically heterogeneous mice. The animals were given the agents daily in their food for their entire lifespan beginning at age 4 months.
These 5 agents were chosen based on consensus opinions of a group of scientists involved in the project based on previous literature.
The study unfortunately concluded that none of the agents had a measurable effect on lifespan.
The authors concluded “none of these five agents had a statistically significant effect on life span of male or female mice, by log-rank test, at the concentrations tested.”