The 1,2,4-Triazolo[1,5-a]pyridines are a synthetic chemical class of molecules. A group of researchers created a library of these molecules and screened them for biological activity.  In particular they were looking for an antioxidant. This class of molecules are hetero-aromatic organic compounds and are well known for biological effects, with examples acting as antihypertensive, bronchodilatory, [...]

As organisms live, breath oxygen and metabolize food, they age.  The two are inextricably linked. Metabolic and respiratory processes generates free radicals and reactive oxygen species which damage cells and their contents.  Cells have a large army of proteins that function to reduce this damage and repair damage that occurs.  It is these protein pathways slow aging. It is known that proteins [...]

The recent report by Moussa et al has taken the Internet by sensation.  They showed rather convincingly that chronic daily oral consumption of C60 fullerene by Wistar rats almost doubled both mean and maximal lifespan compared to control. The oldest lived rat in the C60 group actually lived to 66 months which appears to be a record. C60 is commonly known as a buckyball and is a pure carbon molecule [...]

There is a large body of scientific evidence that oxygen-induced damage of cellular components underlies the aging process. As a result of this work may people attempt to thwart aging by consuming food and other compounds that act as anti-oxidants. Though intellectually satisfying, it is possible this practice might have little effect or even be detrimental.  It is likely that cells bolster and fortify [...]

Oxidative stress and damage is often considered the cornerstone for development of diseases, cancer, and the aging process itself. The theory goes that metabolism of oxygen by cells leads to reactive oxygen species, or free radicals, which go on to damage the content of the cells. As the damage accumulates, the cells become cancerous or senescent, and the organism ages. Now scientists have premiered [...]